Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulatedgene products involved in cell survival, proliferation, invasion, andinflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis.

Blood. 2008 May 15;111(10):4880-91. Epub 2008 Mar 18.

Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferasesuppresses expression of nuclear factor-kappaB-regulatedgene products involved in cell survivalproliferationinvasion, andinflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinaseleading to potentiation of apoptosis.


Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, USA.

Fig 4A - last 2 lanes on the right (AA30 and 60) are cloned.

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